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Translational Research - Biofilms

Tooth Biofilm Model

Engineered Tooth Model - Hydroxyapatite (HA)

Hydroxyapatite (#5 bead) is used to create an enamel-like surface on the CBD (Calgary Biofilm Device); with pre-conditioning, a pellicle-like co-surface enhances mono or multi-species biofilms with clinical dental isolates (Mountain State Oral-Facial Microbiology Laboratory ).

References:

Ceri, H. Olson, M.E., Storey, D.G. and Morck, D.W. (2005) Chapter 13.  Biofilm Susceptibility Testing: The Need for a Minimal Biofilm Eradication Concentration (MBEC) Assay. In Biofilm infectious, roles of antibiotic tolerance and resistance, Pace, J., Rupp, M., and Finch, R. Editors. CRC Press, Florida, USA pp 253-266.

Ceri, H., Olson, M.E., Storey, D. And Morck, D. (2004). Methods for Biofilm Study and Assays for Biofilm Suscpebility and Target Recognition: Approaches to Deal with the Biofilm Mode of Life. In Advances in Biofilm Science and Engineering. Jordan, R., Williams, D., and Charaf, U. Editors. Cytergy Publishing, Bozeman Montana pp. 53-85.